Amino-acid Uptake After Meat Protein Intake

Not Applicable

Completed

• Conditions: Amino Acid Metabolism
• Interventions: Dietary Supplement: Meat protein absorption

• Registration Number: NCT03301337
• Lead Sponsor: Bispebjerg Hospital

Brief Summary

The purpose of the project is to provide evidence for the use of hydrolysed meat protein (HMP) as a protein supplement for elderly who has difficulty meeting the recommended daily protein intake.

The study will investigate how the meat protein derived amino acids (from either HMP, steak or minced meat) are absorbed and released into the blood circulation of elderly persons. Hereby, the study will explore the the anabolic potential of HMP compared with common meat products.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-09-28
• Study First Submitted QC: 2017-10-03
• Study Start: 2017-10-04
• Study First Posted: 2017-10-04
• Primary Completion: 2018-01-30
• Study Completion: 2019-10-30
• Status Verified: 2022-11
• Last Update Submitted: 2022-11-18
• Last Update Posted: 2022-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Healthy
• Untrained

Exclusion Criteria

• below 65 years of age
• BMI above 30
• Smokers
• Vegetarians
• Subjects with diabetes or other metabolic diseases
• Medical treatment affecting protein synthesis
• Gastro-intestinal problems, reduced liver or kidney function, elevated blood pressure, atherosclerosis
• More than 5 ours regular physical activity per week (except physical activity related to commuting)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Hydrolyzed meat protein	Meat protein absorption	D5-phenylalanine intrinsically labelled hydrolyzed meat protein (0.6 g per kg lean body mass), which will be consumed together with a full meal.
Minced Meat	Meat protein absorption	D5-phenylalanine intrinsically labelled hydrolyzed meat protein (0.6 g per kg lean body mass), which will be consumed together with a full meal.
Beef	Meat protein absorption	D5-phenylalanine intrinsically labelled hydrolyzed meat protein (0.6 g per kg lean body mass), which will be consumed together with a full meal.

Primary Outcome Measures

Name	Time	Method
D5-phenylalanine appearance	5 hours	D5-phenylalanine appearance in the blood circulation after meal consumption

Secondary Outcome Measures

Name	Time	Method
Insulin concentration	5 hours	Insulin concentration in the blood circulation after meal consumption

Trial Locations

Locations (1)

Institute of Sports Medicine Copenhagen; 🇩🇰 Copenhagen, Denmark