NCT03669796已完成不适用
A Study of the Effects of Marine Protein Hydrolysate as Dietary Supplement on the Regulation of Postprandial Blood Glucose Metabolism in Healthy Subjects
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 41
- 试验地点
- 2
- 主要终点
- Glucose
研究概览
简要总结
The aim of this study is to investigate the potential effect of a marine protein hydrolysate (MPH) supplement before a meal on postprandial glucose tolerance in healthy subjects, to achieve more knowledge on this presumed beneficial, blood glucose lowering effect
详细描述
To further investigate the effects of MPH in a single dose of 20 mg/kg of body weight on postprandial blood glucose, insulin and GLP-1 (as markers of glucose metabolism) in healthy, active middle-aged to elderly subjects - age 40-65 years.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 40 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Signed informed consent
- •Body mass index (BMI) 20-30
排除标准
- •Suspected allergies against fish or shellfish
- •Low or unstable blood pressure
- •Diabetes mellitus, treated pharmacological
- •Chronic diseases or therapies that is likely to interfere with the evaluation of study results
- •Acute infections (may be reconsidered for inclusion at a later time)
- •Allergic to milk, confirmed diagnose
- •Pregnancy
- •Women who are breast-feeding infants
- •Inability or unwillingness to comply with the requirements of study procedures
结局指标
主要结局
Glucose
时间窗: First sample fasting baseline, thereafter repeated samples every 20 minutes (i.e.20, 40, 60, 80, 100,120,140 minutes after baseline), last at 200 minutes after baseline.
Postprandial glucose (mmol/L) change on each day of intervention
次要结局
- Insulin(First sample fasting baseline, thereafter repeated samples every 20 minutes (i.e.20, 40, 60, 80, 100,120,140 minutes after baseline), last at 200 minutes after baseline)
- Hormon 1(First sample fasting baseline, thereafter repeated samples (i.e.20, 40, 60, 100 minutes after baseline), last at 200 minutes after baseline)
- Visual analogue scale (VAS)(First (baseline) symptomscore (as described above) measured fasting , thereafter repeated symptom score i.e. at 20, 40 minutes after baseline, last symptom score measure at 200 minutes after baseline)
- KANE, symptom score(First (baseline) symptom score (as described above) measured fasting and the next measure at 200 minutes after baseline)
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Marine Protein Hydrolysate as Dietary Supplement in Irritable Bowel SyndromeIrritable Bowel SyndromeNCT03801057Helse Møre og Romsdal HF40
已完成
不适用
Effects of Hydrolysed Porcine Proteins on Muscle Protein Synthesis and AppetiteHungerSatiety ResponseProtein SynthesisNCT02477410University of Copenhagen21
招募中
1 期
Effect of tuna-derived protein hydrolysate on endothelial dysfunction of overweight and obesityHealthy conditionTunaProtein hydrolysateEndothelial dysfunctionOverweightObesityTCTR20230621002Program Management Unit Competitiveness (PMUC)120
已完成
不适用
Amino-acid Uptake After Meat Protein IntakeAmino Acid MetabolismNCT03301337Bispebjerg Hospital12
已完成
不适用
Efficacy of Marine By-product Hydrolysate on the Reduction of Atopic Dermatitis SymptomsEczemaAtopic DermatitisNCT06268847Abyss Ingredients92