Biological effects of oral antimicrobial on systemic bacterial infection caused by full-mouth scaling and root planning: a randomized controlled clinical trial
Not Applicable
- Conditions
- Moderate to severe chronic periodontitis
- Registration Number
- JPRN-UMIN000008411
- Lead Sponsor
- iigata University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1. Persons who had received scaling and root planing within the previous 6 months. 2. Persons who had taken systemic antibiotics or anti-inflammatory drugs within 3 months before experiment. 3. Persons who had severe systemic diseases. 4. Persons who is known or suspected hypersensitivity or intolerance to macrolide antibiotic. 5. Smoker 6. Persons who is suspected of having aggressive periodontitis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cytokine expression level in serum
- Secondary Outcome Measures
Name Time Method Blood endotoxin level Cytokine expression level in gingival crevicular fluid