A Study of Hemodynamic Cardiopulmonary Exercise for CHD

Not Applicable

Recruiting

Brief Summary: The purpose of this study is to compare the difference in the ability to detect hemodynamic abnormalities between invasive hemodynamic assessments performed at rest versus exercise, to assess the correlation between invasive and noninvasive (Doppler-derived) rest-exercise hemodynamic indices and to compare the association between indices of disease severity and hemodynamic abnormalities identified at rest versus exercise.

Recruitment & Eligibility

Inclusion Criteria

Exclusion Criteria

Arm && Interventions

Group	Intervention	Description
Patients Undergoing Clinically indicated Cardiac Cath	Cardiac Cath	-

Primary Outcome Measures

Name	Time	Method
Change in right ventricular free-wall strain from rest to peak exercise	Baseline	Change in right ventricular free-wall strain will be measured in Δ%
Change in pulmonary vascular resistance from rest to peak exercise	Baseline	Change in pulmonary vascular resistance will be measured in ΔWoods Units
Change in left ventricular end-systolic elastance from rest to peak exercise	Baseline	Change in left ventricular end-systolic elastance will be measured in ΔmmHg/mL
Change in systemic vascular resistance from rest to peak exercise	Baseline	Change in systemic vascular resistance will be measured in ΔWoods Units
Change in Left ventricular cardiac output from rest to peak exercise	Baseline	Change in left ventricular cardiac output will be measured in ΔL/min
Change in right ventricular cardiac output from rest to peak exercise	Baseline	Change in right ventricular cardiac output will be measured in ΔL/min

Secondary Outcome Measures

Name	Time	Method

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