rine Biomarkers in Cirrhotic Patients with Acute Kidney Injury

Not Applicable

Recruiting

• Conditions: Acute kidney injury; Cirrhosis; Novel biomarker

• Registration Number: TCTR20180905002
• Lead Sponsor: Rachadapisek Sompot Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-09-05
• Study Completion: 2019-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 107

Inclusion Criteria

1. Hospitalized cirrhotic patients with risk of acute kidney injury

Exclusion Criteria

1. Chronic kidney disease or need renal replacement therapy
3. Post renal acute kidney injury or acute glomerulonephritis or acute interstitial nephritis
4. Liver or kidney transplant
5. Need for immunosuppressive drug other than for treatment of severe alcoholic hepatitis
6. Pregnancy

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diagnosis of acute kidney injury by urine LFABP and NGAL compared with serum creatinine Up to 7 days of admission Level of urine LFABP and urine NGAL on the day of acute kidney injury diagnosed by serum creatinine

Secondary Outcome Measures

Name	Time	Method
Diagnosis of hepatorenal syndrome and acute tubular necrosis by urine LFABP and NGAL Up to 7 days of admission Level of urine LFABP and urine NGAL on the day of hepatorenal syndrome and acute tubular necrosis di