Assessing the effects of positive expectations through open label suggestions on itch
Completed
- Conditions
- Not applicableHet onderzoek wordt bij gezonde proefpersonen uitgevoerd. Uitkomsten uit deze lijn van onderzoek bieden nieuwe handvatten voor verklaringsmodellen en therapeutische interventies voor aandoeningen waarbij jeuk een symptoom is.
- Registration Number
- NL-OMON53166
- Lead Sponsor
- niversiteit Leiden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 92
Inclusion Criteria
Between 18 and 35 years old; good understanding of written and spoken Dutch
Exclusion Criteria
Refusal to give written informed consent; severe somatic or psychological morbidity (e.g. heart and lung diseases, or DSM-IV psychiatric disorders) that would adversely affect participant*s safety or study protocol; current chronic itch or pain complaints; current use of analgesics, anti-inflammatory drugs, antihistamines, antibiotics; pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary study parameter is self-reported mean itch during histamine<br /><br>iontophoresis. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary study outcomes include wheal size, flare response, skin temperature<br /><br>and self-reported skin condition following histamine iontophoresis, as well as<br /><br>scratching behaviour. In addition, effects on positive and negative affect and<br /><br>generalized expectations will be explored. The possible influence of<br /><br>psychological parameters on outcomes will be explored as well. </p><br>