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Atorvastatin Study For The Treatment Of High Cholesterol In Patients From Thailand

Phase 4
Completed
Conditions
Dyslipidemias
Interventions
Registration Number
NCT00647543
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Brief Summary

The purpose of this study is to evaluate the efficacy of atorvastatin in lowering cholesterol on patients from Thailand with high cholesterol.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
242
Inclusion Criteria
  • Dyslipidemic patients who were eligible for lipid lowering therapy
  • Willingness to follow study diet for 1 month prior to screening and for the duration of the study
Exclusion Criteria
  • Use of other lipid lowering agents (6-week washout period)
  • Uncontrolled high blood pressure
  • Impaired liver function

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
High RiskAtorvastatin-
Low RiskAtorvastatin-
Medium RiskAtorvastatin-
Primary Outcome Measures
NameTimeMethod
Percentage of patients who achieved low-density lipoprotein cholesterol (LDL-C) targetWeek 8
Secondary Outcome Measures
NameTimeMethod
Change and percent change from baseline in high-density lipoprotein cholesterol (HDL-C)Weeks 2, 4, and 8
Change and percent change from baseline in LDL/HDL ratioWeeks 2, 4, and 8
Change and percent change from baseline in total cholesterolWeeks 2, 4, and 8
Change and percent change from baseline in triglyceridesWeeks 2, 4, and 8
Adverse events and laboratory test changesWeeks 2, 4, and 8
Percentage of patients who achieved LDL-C targetWeeks 2 and 4, and Week 8 with 1 step titration
Change and percent change from baseline in LDL-CWeeks 2, 4, and 8

Trial Locations

Locations (1)

Pfizer Investigational Site

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