Retrospective clinical study for albumin leakage and survival in hemodialysis and online hemodiafiltratio
Not Applicable
- Conditions
- Patients with end-stage renal failure undergoing hemodialysis
- Registration Number
- JPRN-UMIN000045112
- Lead Sponsor
- Social medical corporation Kawashimakai
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 780
Inclusion Criteria
Not provided
Exclusion Criteria
1) Under 20 years of age 2) Dialysis conditions (dialysis method, dilution method, substitution volume, membrane material) between April 1, 2017 and June 30, 2017, which are different from those as of July 1, 2017 3) Blood purification methods other than HD or OHDF 4) Dialysis frequency below 3 sessions per week or dialysis time below 3 hour per session 5) Substitution volume of less than 60 L in pre-OHDF and less than 8 L in post-OHDF 6) Pregnant or lactating patients 7) Missing values of covariatesat at the start of the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of all-cause mortality during 3 yearss for estimated albumin leakage (high vs. low) in HD and OHDF
- Secondary Outcome Measures
Name Time Method 1. Comparison of all-cause mortality during 3 years in groups divided by estimated albumin leakage (high and low) and serum albumin concentration (high and low) in HD and OHDF 2. Direct comparison of HD and OHDF on all-cause mortality during 3 years divided by the same ranges of estimated albumin leakage (less than 2.5g, 2.5g or more and less than 5.0g, 5.0g or more and less than 7.5g) 3. Direct comparison of estimated albumin leakage and the substitution volume in pre-OHDF and post-OHDF on all-cause mortality during 3 years