study of comparison of changes in the hemodynamic responses to laryngoscopy and intubation after giving intravenous esmolol and diltiazem in elective surgeries under general anesthesia. It is a randomised double blind interventional study conducted at SMS hospital, jaipur
- Conditions
- Health Condition 1: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Registration Number
- CTRI/2020/06/026148
- Lead Sponsor
- Department of anesthesiologySMS Medical college
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients willing to give informed written consent
2. Patients with ASA grade 1 and 2
3. Age group-20-50 years
4. Patients scheduled for elective surgeries under general anesthesia with larnygoscopy and endotracheal intubation
1. Patients unwilling to participate in the study.
2. Patients with difficult airway i.e more than 1 attempt of intubation performed or more than 15 seconds intubation time taken.
3. Patients having known allergy to the drugs used in the study.
4. Patients withhistory of any medications affecting heart rate and blood pressure.
5. Patients with history of any severe cardiovascular, respiratory, endocrine, renal,hepatic, neurotic or psychiatric illness .
6. Patients with baseline heart rate <60bpm.
7. Patients with ASA grade -3,4,5.
8. Patients with bleeding disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess and compare changes in Hemodynamic parameters- <br/ ><br>Heart rate, Systolic blood pressure,Diastolic blood pressure, Mean arterial blood pressure in both the study groups <br/ ><br>Timepoint: baseline values, after test drugs, before laryngoscopy, 1minute, 3minutes, 5minutes, 10minutes after intubation <br/ ><br>
- Secondary Outcome Measures
Name Time Method To look for any side effects- hypotension, bradycardia, headache, flushing or any other complaint in both the study groupsTimepoint: 1hour, 6hours, 12hours and 24 hours post operatively