Comparison of adding Tamoxifen or Gonadotropin to Clomiphene for induction ovulation in Polycystic Ovary Syndrome (PCOS) patients resistance to Clomiphene
Phase 2
- Conditions
- Polycystic Ovary Syndrome.Polycystic Ovary Syndrome
- Registration Number
- IRCT138904121760N8
- Lead Sponsor
- Vice Chancellor for Research and Technology, Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 200
Inclusion Criteria
PCOS Clomiphen citrate resistance Patients with age between 18 and 35 years, years period of infertility between 1.5-5 yr and BMI between 19-35. Exclusion criteria: hyperprolactinaemia, hypercorticism or thyroidism, pelvic pathology or surgery, infertility factor other than anovulation excluded.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Dominant follicle. Timepoint: 12 -16 menstrual cycle. Method of measurement: sonography.;Rate ovulation. Timepoint: 36-38 days after HCG injection. Method of measurement: sonography.;Endometrial thickness. Timepoint: at HCG injection day. Method of measurement: sonography.
- Secondary Outcome Measures
Name Time Method Occurrence of pregnancy. Timepoint: 25 days after HCG injection. Method of measurement: sonography.