Can prophylactic use of ondansetron prevent the incidence of pruritus (itching) and postoperative nausea and vomiting caused by morphine used during anesthesia?
Not Applicable
- Conditions
- Health Condition 1: null- Parturients of ASA class I or II physical status scheduled for cesarean delivery under spinal anesthesia.
- Registration Number
- CTRI/2015/01/005362
- Lead Sponsor
- Dr Ram Bhakta Koju
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Applicable
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Parturients of American Society of Anesthesiologists (ASA) class I or II physical status scheduled for caesarean delivery under spinal anaesthesia.
Exclusion Criteria
1) Patients with known allergy to ondansetron, bupivacaine or morphine.
2) Patients with pruritogenic systemic disease, a coexisting skin disorder or preexisting pregnancy induced pruritus.
3) Patients with any contraindication for spinal anesthesia.
4) Patients who refused to participate in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Incidence of pruritus and post operative nausea/vomiting <br/ ><br>Timepoint: Every 15 minutes for first 4 hours followed by 8 and 24 hours post surgery <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1) Onset and Duration of pruritus <br/ ><br>2) Severity of pruritus <br/ ><br>3)Severity of post operative nausea / vomitingTimepoint: Every 15 minutes for first 4 hours followed by 8 and 24 hours post surgery