A study to see the effect of a drug, ondansetron on blood pressure during caesarean section.
Not Applicable
- Conditions
- Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and deliveryHealth Condition 2: O00-O9A- Pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2022/04/041661
- Lead Sponsor
- Dr Manjulata Tandan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Age 18-40 years
2. BMI <35kg/m2
3. ASA Physical status â??Ð?Ð?
4. Term parturients undergoing elective caesarean
section under subarachnoid .
block.
5. Height : 140- 170cm
Exclusion Criteria
1.Parturients refusal to participate.
2.Contraindication to spinal anaesthesia.
3.Insufficient blockade requiring supplementation
of anaesthesia.
4.Any comorbidities like Pre-existing or Pregnancy
induced Hypertension ,Cardiovascular or
Cerebrovascular disease, Gestational Diabetes
Mellitus, renal impairment, severe liver
disease, hypo or hyperthyroidism.
5. Spinal anaesthesia converted to General
Anaesthesia.
6. Patients on selective serotonin reuptake
inhibitor.
7. Allergy to Ondansetron.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To measure the incidence of spinal induced hypotension with or without iv ondansetron premedicationTimepoint: At every 2 minutes after administration of spinal anaesthesia till 20 minutes and every 5 minutes there after till completion of surgery <br/ ><br>
- Secondary Outcome Measures
Name Time Method To estimate total number of boluses of iv mephentermine required for correction of hypotension with or without iv ondansetron premedication, <br/ ><br>Incidence of nausea,vomiting and shivering <br/ ><br> <br/ ><br>Neonatal APGAR Score <br/ ><br> <br/ ><br>Timepoint: At every 2 minutes after administration of spinal anaesthesia till 20 minutes and every 5 minutes there after till completion of surgery <br/ ><br>