Effect of Ondansetron on maternal blood pressure and neonatal parameters when given before spinal anaesthesia during caesarean sectio
Phase 4
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/03/064356
- Lead Sponsor
- Rajendra Institute Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patient consent
Pregnant females between 18 to 45 years of age posted for elective caeserean section in Rajendra Institute of Medical Sciences
Exclusion Criteria
Emesis gravidarum
Preeclampsia
Morbid obesity
Contraindications to spinal anesthesia,
allergy or intolerance to local anaesthetic agents or other
agents used for the study.
Presence of co-morbidities like severe anaemia, uncontrolled
diabetes mellitus, asthma, uncontrolled hypertension, severe cardiac
disease
Patient’s belonging to ASA III and above
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Changes in Systolic blood pressure <br/ ><br>2. Changes in diastolic blood pressure <br/ ><br>3.Changes in mean arterial pressure <br/ ><br>4.Changes in Heart RateTimepoint: 1.From time of induction, every 2 minutes till 20minutes and thereafter every 5minutes till 50minutes. <br/ ><br>2.From time of induction, every 2 minutes till 20minutes and thereafter every 5minutes till 50 minutes. <br/ ><br>3. From time of induction, every 2 minutes till 20minutes and thereafter every 5minutes till 50minutes. <br/ ><br>4.From time of induction, every 2 minutes till 20minutes and thereafter every 5minutes till 50minutes.
- Secondary Outcome Measures
Name Time Method 1.Fetal umblical artery pH,lactate,bicarbonate, sodium, potassium, chloride and calcium levels by arterial blood gas analysis. <br/ ><br>2. APGAR scoreTimepoint: 1. Immediately after delivery (ideally within 3 minutes) <br/ ><br>2. At 1 minute, 3 minute, 5minute and 10minutes post delivery