Effects of Ondansetron and Clonazepam on Nausea and Vomiting after Laparoscopic Cholecystectomy
Phase 1
Recruiting
- Conditions
- aparoscopic cholecystectomy.
- Registration Number
- IRCT20090912002445N6
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
between 18 and 65 years of age.
Having American Society of Anesthesiologists (ASA) physical status of I or II
Exclusion Criteria
Patients with body mass index (BMI) more than 30 kg/m2
history of previous severe Post-Operative Nausea and Vomiting (PONV)
history of motion sickness
significant gastrointestinal problems
recent antiemetic drugs consumption
smokers
impaired kidney or liver functions and menstruating
pregnant or lactating females
migraine or cluster headaches
mental retardation
psychiatric disorder
chronic alcohol consumption
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ausea`. Timepoint: 1, 3, 6, 12 and 24 hours after the operation. Method of measurement: 10-measure visual analogue scale (VAS).;Severity of pain. Timepoint: 1, 3, 6, 12 and 24 hours after the operation. Method of measurement: 10-measure visual analogue scale (VAS).;Vomiting. Timepoint: First 12 hours after the operation. Method of measurement: Record of vomiting incidence.
- Secondary Outcome Measures
Name Time Method