Adjunctive Precision 40Hz Gamma Transcranial Alternating Current Stimulation on Negative and Cognitive Symptoms in Schizophrenia:A Sham-Controlled EEG Study

Central Institute of Psychiatry0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年5月29日

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•1. Diagnosis of Schizophrenia using Diagnostic Criteria for Research (DCR) of International Classification of Disease-10th edition (ICD-10, World Health Organization, 1993).
•2. Aged between 18- 60 years, right-handed individuals of either sex, giving informed consent.
•3. An illness of duration more than 2 years & on stable dose of antipsychotics.
•4. The Positive and Negative Syndrome Scale for Schizophrenia (PANSS) negative symptoms score of more than 15.
•5. Scale for Assessment of Negative Symptoms (SANS) score more than 20.
•6. Calgary Depression Scale for Schizophrenia (CDSS) score less than 7.
•7. Score less than or equal to 25 on screening with Hindi Montreal Cognitive Assessment Test (Hindi MoCA).

•1. Presence of comorbid neurological or other psychiatric disorder(s).
•2. Patients with comorbid substance dependence in the last 6 months, except nicotine and caffeine.
•3. Subjects who have received ECT in the past one month.
•4. Patients with contraindications to MRI like pacemakers, metallic implants etc.

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