Manchester Adolescent Varicocele Study

Not Applicable

• Conditions: Varicocele; Urological and Genital Diseases; Scrotal varices

• Registration Number: ISRCTN57825419
• Lead Sponsor: Central Manchester Foundation NHS Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-11-24
• Last Update Posted: 9 October 2023
• Study Completion: 2026-01-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: Male
• Target Recruitment: 126

Inclusion Criteria

1. Between ages of 14-17 years at recruitment to study
2. Have a clinically detectable varicocele
3. High grade reflux on Doppler ultrasound (grade 2 or 3)

Exclusion Criteria

1. Children younger than 14 years of age or older than 17 years at time of recruitment to study
2. Testicular growth arrest
3. Previous inguinal surgery
4. Orchitis
5. Epididymo-orchitis
6. Testicular torsion
7. Endocrinological disorders

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> To compare the trend in semen analysis between the two groups:<br> 1. Percentage normal semen quality (according to the WHO criteria)<br> 2. Percentage of motile sperm<br> 3. Mean concentration of sperm (million per millilitre)<br>

Secondary Outcome Measures

Name	Time	Method
Difference in testicular volume (mls) between the affected side (with the varicocele) and the contralateral testis. The testicular sizes will be measured every 6 months.