Postoperative pain management after lower abdominal suegeries
- Conditions
- Health Condition 1: K639- Disease of intestine, unspecified
- Registration Number
- CTRI/2021/05/033316
- Lead Sponsor
- Dr S N Medical College Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
ASA I and II with lower abdominal surgery under general anesthesia, surgical time up to 2 hours.
Patients planned for postoperative mechanical ventilation or regional anesthesia/analgesia, perioperative gabapentin, magnesium, or nitrous oxide use, pregnancy or breastfeeding, morbid obesity (BMI >= 35 kg/m2 ), allergy to study medications, contraindication to lidocaine (severe cardiac arrhythmia) or ketamine (psychiatric disorder, substance abuse, uncontrolled hypertension, pulmonary hypertension, increased intracranial or intraocular pressure, use of MAO inhibitors), chronic preoperative opioid use (>= 90 morphine mg equivalents per day for > 3 months), significant preoperative hepatic dysfunction (ALT or AST > 5 times normal or planned liver transplantation), preoperative cardiac failure (left ventricular ejection fraction <= 40%), unable to communicate study instructions.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare total mean opioid consumption(fentanyl) in first 24 hours postoperatively in three groups receving lignocaine, ketamine and normal saline.Timepoint: first 24 hours
- Secondary Outcome Measures
Name Time Method 1.VAS scores <br/ ><br>2.Time to request first analgesic after surgery <br/ ><br>3.Hemodynamic parameters <br/ ><br>4.Post-operative hospital length of stay (days). <br/ ><br>5.Adverse effects <br/ ><br>Timepoint: 24 hours