COMPARISON OF EFFICACY OF THREE ADJUVANT DRUGS ADRENALINE, CLONIDINE AND DEXMEDETOMIDINE WHEN USED WITH LIGNOCAINE HYDROCHLORIDE FOR LOCAL ANAESTHESIA FOR SURGICAL REMOVAL OF IMPACTED MANDIBULAR THIRD MOLAR
- Conditions
- Health Condition 1: K011- Impacted teeth
- Registration Number
- CTRI/2022/12/048281
- Lead Sponsor
- Sharad Pawar Dental College And Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1) Individuals with ASA Gr I status
2) Individuals between 18 to 40 years
3) Presence of at least one asymptomatic impacted mandibular third molar having moderate to very difficult ,difficulty index ( Modified Pedersonâ??s Scoring )
1. History of drug dependence
2. Patients with systemic disease such as HTN, DM, blood dyscrasias, immunocompromised status.
3. Patients who chronic smokers
4. Patients on cardio-selective antihypertensive drugs
5. Patients with allergy to local anesthetic agents used in the study
6. Pregnant and nursing mothers
7. Females on oral contraceptives
8. Patients undergoing treatment with antibiotics, anti-inflammatory drugs
9. Presence of any local infection like pericoronitis/pterygomandibular space infection
10. Presence of any chronic facial pain on the side of intervention
11. Radiologic evidence of Inferior alveolar canal approximation
12. Patients with Congenital Heart Disease.
13. Patients who are have any psychiatric illness.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Onset of anesthesia <br/ ><br>2) Depth of anesthesia <br/ ><br>3) Hemodynamic parameters <br/ ><br>4) Duration of postoperative analgesiaTimepoint: at Baseline, after 30 minutes,after 1 hour
- Secondary Outcome Measures
Name Time Method Hemodynamic parametersTimepoint: at Baseline, after 15 minutes, 30 minutes,60 minutes and 120 minutes