Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Change in stroke volume
研究概览
简要总结
In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration.
It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.
详细描述
In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration.
It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •0 to < 18 years old
- •Undergoing surgery at Boston Children's Hospital under general anesthesia
- •mechanically ventilated with an endotracheal tube
- •Monitored with an indwelling radial arterial catheter as part of the anesthetic plan for the scheduled surgical procedure
排除标准
- •Prematurity
- •Low birth weight
- •Congenital heart disease
- •Left or right ventricular dysfunction
- •Cardiac arrhythmia
- •Pulmonary hypertension
- •Preoperative parenchymal or interstitial lung disease
- •Intracranial hypertension
- •Poor transthoracic acoustic window
- •Allergy to ultrasound transmission gel
- •Need for single lung ventilation
- •Systemic hypertension on antihypertensive medications
结局指标
主要结局
Change in stroke volume
时间窗: immediately before and after each intervention
Evaluate Lung Recruitment Maneuver as a means to predict fluid responsiveness in mechanically ventilated pediatric patients in the operating room.
次要结局
- Change in arterial compliance effect on Pulse Pressure Variation (%)(immediately before and after each intervention)
- Change in arterial compliance effect on Systolic Pressure Variation (mmHg)(immediately before and after each intervention)
- Change in arterial compliance effect on Plethysmographic Variability Index (%)(immediately before and after each intervention)
研究者
Viviane Nasr
Cardiac Anesthesiologist
Boston Children's Hospital