Comparison of Postoperative Aqueous Flare After 20G Versus 23G Pars Plana Vitrectomy

Not Applicable

• Conditions: Macular Hole; Macular Pucker
• Interventions: Procedure: 23G vitrectomy; Procedure: 20G Vitrectomy

• Registration Number: NCT01969929
• Lead Sponsor: University of Cologne

Brief Summary

To compare postoperative inflammation and breakdown of blood-retinal barrier as measured by a laser flare-cell meter in 20G versus 23G vitrectomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-10
• Study First Submitted: 2013-10-18
• Study First Submitted QC: 2013-10-21
• Study First Posted: 2013-10-25
• Status Verified: 2015-05
• Last Update Submitted: 2015-05-29
• Last Update Posted: 2015-06-01
• Primary Completion: 2015-10
• Study Completion: 2015-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

age > 18 years macular hole macular pucker willing to perform follow up written signed consent

Exclusion Criteria

other relevant eye disease: retinal detachment, provect cataract, diabetic retinopathy, AMD, relevant glaucoma, pre-surgery except for cataract surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
23G	23G vitrectomy	23G transconjunctival sutureless vitrectomy
20G	20G Vitrectomy	20G vitrectomy with scleral and conjunctival sutures for closure

Primary Outcome Measures

Name	Time	Method
Alteration of aqueous flare between preoperative and 3-week-postoperative time point	3 weeks

Secondary Outcome Measures

Name	Time	Method
Visual acuity change	3 weeks
Closure of Macular hole	3 weeks

Trial Locations

Locations (1)

Center of Ophthalmology, University of Cologne; 🇩🇪 Cologne, NRW, Germany