Ophthalmic Artery Resistance Index After Peribulbar Block in the Presence of Epinephrine

Not Applicable

Completed

• Conditions: Peribulbar Block; Ophthalmic Artery
• Interventions: Drug: Epinephrine

• Registration Number: NCT04153123
• Lead Sponsor: Federal University of Minas Gerais

Brief Summary

Evaluate ophthalmic artery flow by echo-Doppler before and after peribulbar block with lidocaine in presence or absence of epinephrine.

Detailed Description

There are controversies regarding the ophthalmic artery (OA) flow after peribulbar block with the addition of epinephrine. Therefore, we aimed to evaluate OA flow by echo-Doppler before and after peribulbar block with lidocaine in presence or absence of epinephrine.

Fifty-six patients that were eligible for cataract phacoemulsification surgery were selected. Patients were divided into two groups: group 1 - Peribulbar block with lidocaine and 1/200.000 epinephrine; group 2 - Peribulbar block with lidocaine in the absence of epinephrine. The resistance index (RI) of OA was evaluated using echo-Doppler before and 10 min after the peribulbar block.

Study Timeline

• Study Start: 2013-12-01
• Primary Completion: 2014-05-31
• Study Completion: 2014-05-31
• Status Verified: 2019-11
• Study First Submitted: 2019-11-03
• Study First Submitted QC: 2019-11-05
• Last Update Submitted: 2019-11-05
• Study First Posted: 2019-11-06
• Last Update Posted: 2019-11-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

• American Society of Anesthesiologists (ASA) I, II or III physical status classification
• Cataract surgery

Exclusion Criteria

• glaucoma
• diabetic retinopathy
• previous eye surgery in the same eye
• ocular trauma
• allergic to any protocol medication
• uncooperative patients or cognitive difficulties
• axial eye diameter of less than 21.0 mm or greater than 25.5 mm.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lidocaine with epinephrine	Epinephrine	Peribulbar anesthesia with lidocaine and epinephrine

Primary Outcome Measures

Name	Time	Method
Artery resistance index of ophthalmic artery	Change on resistance index 10 minutes after peribulbar anesthesia	The resistance index (RI) of OA was evaluated using echo-Doppler before and 10 minutes after the peribulbar block.

Trial Locations

Locations (1)

Universidade Federal de Minas Gerais, Faculdade de Medicina, Departamento de Cirurgia.; 🇧🇷 Belo Horizonte, Minas Gerais, Brazil