Effects of a Nurse-delivered Cognitive Behaviour Therapy on Adherence and Depressive Symptoms in HIV Infected Persons of South Korea

Not Applicable

• Conditions: HIV Infections
• Interventions: Behavioral: Cognitive Behavioral Therapy

• Registration Number: NCT03823261
• Lead Sponsor: Yonsei University

Brief Summary

Cognitive behaviour therapy (CBT) has repeatedly been found to effectively treat depression in adult populations, and CBT for adherence and depression (CBT-AD) is an effective treatment for improving depressive symptoms and medication adherence in the context of various chronic health conditions, including HIV-infection. However, the effects of CBT have not been evaluated in South Korea. Even though HIV infection is currently a controllable disease for patients on successful antiretroviral therapy, people living with HIV (PLWH) are still suffering from internal and external stigmatization in many Asian countries, including South Korea. It is not clear whether CBP-AD would be successful intervention among Asian countries with cultural background of strong stigmatization on HIV/AIDS. We plan to do survey on facilitators or barriers to patients and providers to identify significant contextual factors in South Korea. Demographic data and clinical data including CD4+ T cell counts, viral loads, and antiretroviral therapy regimens will be collected, as well.

Specialists such as psychiatrist or clinical psychologist would be the best provider for CBT intervention. However, an effective and feasible therapy model should be integrated into primary HIV care in South Korea. Medical personnel within most HIV clinics in South Korea include infectious diseases doctors, clinical nurses, and counselling nurses, but CBT services from psychiatrist or clinical psychologist are not routinely available in many hospitals. Hospital-based counselling services with experienced nurses have been provided in many HIV clinics in South Korea, and the counselling nurses would be feasible providers for CBT intervention of this study. So, we plan to investigate the effects of a nurse-delivered cognitive behaviour therapy.

Detailed Description

Not available

Study Timeline

• Status Verified: 2019-01
• Study First Submitted: 2019-01-22
• Study First Submitted QC: 2019-01-27
• Last Update Submitted: 2019-01-27
• Study First Posted: 2019-01-30
• Last Update Posted: 2019-01-30
• Study Start: 2019-03
• Primary Completion: 2020-01-31
• Study Completion: 2020-02-29

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
CBT	Cognitive Behavioral Therapy	-

Primary Outcome Measures

Name	Time	Method
Level of depression	1 year	Individual patient would be measured by Beck depression inventory.
Level of adherence	1 year	Individual patient would be measured by visual analog scale and pill counting.

Secondary Outcome Measures

Name	Time	Method
Quality of life	1 year	Individual patient would be measured by PozQoL. PozQoL is a tool measuring quality of life among people with HIV.

Trial Locations

Locations (1)

Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University Health System; 🇰🇷 Seoul, Korea, Republic of