The effects of additional protein intake on muscle strength and physical performance in physically active elderly

Completed

• Conditions: sarcopenie; Muscle strength loss; reduced phyiscal functionality; 10028393

• Registration Number: NL-OMON45732
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

- 65 years or older
- Registered for the Nijmegen Four Days Marches 2017
- Protein intake less than 1.0 gram/kilogram bodyweight/day
- Able to understand and perform the study procedures

Exclusion Criteria

- Type I or type II diabetes (fasted blood glucose level *7,0 mmol)
- Allergic or sensitive for milk proteins, or lactose intolerant.
- Having diagnosed COPD or treatmet with cancer
- Having diagnosed renal insufficiency
- Having diagnosed intestinal diseases influencing the uptake of protein (i.e. active inflammatory bowel disease, Crohn*s disease)
- Use of statins
- Involved in a heavy resistance type exercise program

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcomes are differences in change in muscle strength and physical<br /><br>performance between the intervention and control group after 12 weeks.<br /><br>Moreover, muscle mass will be determined to assess differences between the<br /><br>intervention and control group.<br /><br><br /><br>Primary outcome<br /><br>Maximal voluntary contraction (leg extension strength) of 3 repeated measures<br /><br>(3RM) and physical performance (determined with Short Physical Performance<br /><br>Battery (SPPB)).</p><br>