Study of the influence of a lung recruitment strategy on oxygenation, lung mechanics and dead-space in thoracic surgery

Completed

• Conditions: Thoracic surgery; Surgery

• Registration Number: ISRCTN94238623
• Lead Sponsor: Hospital de Sant Pau (Spain)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-06-01
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Elective adults patients undergoing open thoracic surgery in lateral position requiring one-lung ventilation lasting longer than 40 minutes

Exclusion Criteria

Previous contralateral lobectomy, uncompensated cardiac disease, arrhythmias with hemodynamic repercussions, severe air trapping (residual volume > 150%) and presence of large bullae

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Arterial blood gases<br>2. Volumetric capnography<br>3. Ventilatory and hemodynamic data <br><br>These were recorded at the end of each one of the following study periods:<br>1. TLVbaseline: 5 min after placing the patient in the lateral position during TLV<br>2. TLV20: 20 min after placing the patient in the lateral position during TLV<br>3. OLV20: 20 min after OLV ventilation<br>4. OLV40: 40 min after OLV ventilation<br>5. TLVend: 10 min after re-establishing TLV once pulmonary resection was completed

Secondary Outcome Measures

Name	Time	Method
o secondary outcome measures