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临床试验/CTRI/2025/01/079332
CTRI/2025/01/079332尚未招募4 期

Effect of adding different doses of magnesium sulphate as adjuvant to ropivacaine on the duration of analgesia in upper limb surgeries under supraclavicular brachial plexus blockade-A Randomized controlled study

SRM medical college hospital and research institute1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2025年2月2日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
120
试验地点
1
主要终点
To estimate the total duration of analgesia

研究概览

简要总结

A total of 120 patients belonging to age group 18 years to 65years , ASA class I and II scheduled for upper limb orthopaedic surgeries will be prospectively studied. In this double-blinded randomized control trial, Patients will be randomly allocated into three equal study groups each containing 40 patients.  Group (A) received 24 ml of 0.5 % Ropivacaine+ 1ml Magnesium Sulphate 50 mg (control group)  **Group (B)**received 24 ml of 0.5 % Ropivacaine + 1ml Magnesium Sulphate 100 mg  Group (C) received 24 ml of 0.5% Ropivacaine +1 ml Magnesium Sulphate 150 mg

Usg guided supraclavicular brachial plexus block will be given under usg guidance before surgery

All patients will be assessed for- Onset of sensory and motor blockade, total duration of analgesia, time of first rescue analgesia, postoperative analgesic requirement, and complications due to the technique,  will be recorded.   Data collection will be done by observation and measurement of various parameters

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients undergoing upper limb orthopedic surgeries under USG guided supraclavicular brachial plexus block ,ASA grade I & ASA II and BMI less than30.

排除标准

  • 1.Patient refusal 2.Pregnancy 3.Patients with abnormal Coagulation profiles and coagulopathies 4.Patients with cardiac diseases, chronic kidney diseases, chronic liver diseases, respiratory diseases 5.Patients with allergy to ropivacaine or magnesium sulphate 6.Preexisting musculocutaneous disorder or neuropathies.

结局指标

主要结局

To estimate the total duration of analgesia

时间窗: 1hr,2hr,3hr,4hr,8hr,12hr,16hr,20hr,24hr

次要结局

  • To calculate the time of onset of sensory & motor blockade(To calculate time of first rescue analgesia)

研究者

发起方
SRM medical college hospital and research institute
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Shaheen Khan M

SRM medical college and research institute

研究点 (1)

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