Effect of adding different doses of magnesium sulphate as adjuvant to ropivacaine on the duration of analgesia in upper limb surgeries under supraclavicular brachial plexus blockade-A Randomized controlled study
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- To estimate the total duration of analgesia
研究概览
简要总结
A total of 120 patients belonging to age group 18 years to 65years , ASA class I and II scheduled for upper limb orthopaedic surgeries will be prospectively studied. In this double-blinded randomized control trial, Patients will be randomly allocated into three equal study groups each containing 40 patients. Group (A) received 24 ml of 0.5 % Ropivacaine+ 1ml Magnesium Sulphate 50 mg (control group) **Group (B)**received 24 ml of 0.5 % Ropivacaine + 1ml Magnesium Sulphate 100 mg Group (C) received 24 ml of 0.5% Ropivacaine +1 ml Magnesium Sulphate 150 mg
Usg guided supraclavicular brachial plexus block will be given under usg guidance before surgery
All patients will be assessed for- Onset of sensory and motor blockade, total duration of analgesia, time of first rescue analgesia, postoperative analgesic requirement, and complications due to the technique, will be recorded. Data collection will be done by observation and measurement of various parameters
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients undergoing upper limb orthopedic surgeries under USG guided supraclavicular brachial plexus block ,ASA grade I & ASA II and BMI less than30.
排除标准
- •1.Patient refusal 2.Pregnancy 3.Patients with abnormal Coagulation profiles and coagulopathies 4.Patients with cardiac diseases, chronic kidney diseases, chronic liver diseases, respiratory diseases 5.Patients with allergy to ropivacaine or magnesium sulphate 6.Preexisting musculocutaneous disorder or neuropathies.
结局指标
主要结局
To estimate the total duration of analgesia
时间窗: 1hr,2hr,3hr,4hr,8hr,12hr,16hr,20hr,24hr
次要结局
- To calculate the time of onset of sensory & motor blockade(To calculate time of first rescue analgesia)
研究者
Dr Shaheen Khan M
SRM medical college and research institute
