NL-OMON32932
Withdrawn
Not Applicable
Effect of µ-opioid receptor (MOR) versus N-methyl-D-aspartate receptor (NMDAR) involvement in ketamine and methadone effects in healthy volunteers with special focus on antinociception, sedation, respiratory depression and pupil constriction - KET MET study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- acute pijn
- Sponsor
- eids Universitair Medisch Centrum
- Enrollment
- 48
- Status
- Withdrawn
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •healthy volunteers, aged 18\-45 years.
Exclusion Criteria
- •Obesity (BMI \> 35\); Presence of medical disease (heart\-, lung\-, liver\-, kidney\-, neurologic disease; diabetes m.; pyrosis; diaphragmatic hernia);
- •Presence of psychiatric disease; History of chronic alcohol or illicit drug use;
- •Allergy to study medications.
Outcomes
Primary Outcomes
Not specified
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