Skip to main content
MedPathMedPath Home
Clinical Trials/NL-OMON20544
NL-OMON20544
Not yet recruiting
Not Applicable

Effect of u opioid receptor (MOR) versus N-methyl-D- aspartate(NMDAR) receptor involvement in ketamine and methadone effects in healthy volunteers.

eiden University Medical Centre (LUMC)0 sites48 target enrollmentTBD
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
Conditionsanalgesiarespiratory depressionpijnstillinganalgesieademhalingsdepressie

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
analgesiarespiratory depressionpijnstillinganalgesieademhalingsdepressie
Sponsor
eiden University Medical Centre (LUMC)
Enrollment
48
Status
Not yet recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

/A

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
eiden University Medical Centre (LUMC)

Eligibility Criteria

Inclusion Criteria

  • •48 healthy volunteers of either sex in the range op 18\-45 years.

Exclusion Criteria

  • •1\. Obesity (BMI\>35\);
  • •2\. Presence of medical disease (heart\-,lung\-, liver\-,kidney\-, neurologic disease,diabetes m, pyrosis,diaphragmatic hernia);

Outcomes

Primary Outcomes

Not specified

Similar Trials

Withdrawn
Not Applicable
Effect of µ-opioid receptor (MOR) versus N-methyl-D-aspartate receptor (NMDAR) involvement in ketamine and methadone effects in healthy volunteers with special focus on antinociception, sedation, respiratory depression and pupil constrictioacute pijnnociceptionpain
NL-OMON32932eids Universitair Medisch Centrum48
Completed
Not Applicable
In the blood sample of the patients planned for nasal septoplasty was evaluated the level of opioid analgesic receptor and the relations between the level of receptor and pain score,
ACTRN12619001652167MUZAFFER GENCER120
Active, not recruiting
Phase 1
The effects of opioid receptor antagonism on acute pancreatitis
EUCTR2020-002313-18-DKMech-Sense, Aalborg University Hospital90
Active, not recruiting
Phase 1
The effects of peripheral opioid receptor antagonism on recurrent acute pancreatitisRecurrent acute pancreatitisMedDRA version: 20.0Level: PTClassification code 10033647Term: Pancreatitis acuteSystem Organ Class: 10017947 - Gastrointestinal disordersTherapeutic area: Diseases [C] - Digestive System Diseases [C06]
EUCTR2021-000069-34-DKMech-Sense, Aalborg University Hospital120
Unknown
Not Applicable
MOR and COMT SNP Polymorphism and PainPain Relief
NCT00773760East Tallinn Central Hospital100