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临床试验/NCT03716765
NCT03716765已完成不适用

Locally Injected Vitamin D as a Non-surgical Modality for Periodontal Regeneration of Infrabony Defects: Prospective Study

Cairo University0 个研究点目标入组 20 人开始时间: 2016年1月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
20
主要终点
radiographic interproximal bone level

研究概览

简要总结

vitamin D has great role in bone regenration and soft tissue health. in the past periodontal regeneration was performed using bone graft and barrier membrane

详细描述

there was no previous studies used the locally injected vitamin d in periodontal regeneration. therefore, we intended to study the effect of locally injected vitamin D in peridoontal regerneration in comparison with the conventional surgical technique

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Care Provider, Investigator)

入排标准

年龄范围
20 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • patients with infrabony vertical defects
  • systemically free patients
  • periodontally affected patients

排除标准

  • patients with systemic diseases
  • pregnency

研究组 & 干预措施

non-surgical periodontal regeneration

Experimental

non-surgical periodontal regeneration using locally injected vitamin d to treat the infrabony defect

干预措施: locally injected vitamin D (Dietary Supplement)

surgical peridoontal regeneration

Active Comparator

surgical periodontal regeneration using bone graft and collagen barrier

干预措施: locally injected vitamin D (Dietary Supplement)

结局指标

主要结局

radiographic interproximal bone level

时间窗: 6 months

radiographic interproximal bone level

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

nermin mohammed ahmed yussif

assistant lecturer

Cairo University

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