Prevalence of the progression of maculopathy after drug cessation in eyes with chloroquine retinal toxicity

Recruiting

• Conditions: progression of maculopathychloroquine retinal toxicity; maculopathy; chloroquine; retinal toxicity

• Registration Number: TCTR20230718002
• Lead Sponsor: Faculty of Medicine Siriraj Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-07-18
• Study Completion: 2024-06-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

Patients over age 18 years with diagnosis of chloroquine retinopathy from 2000 to 2016

Exclusion Criteria

1. Patients with coexisting or uncertain retinal or macular diseases from other causes
2. The poor quality of investigation

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Progression of maculopathy after drug cessation in eyes with chloroquine retinal toxicity At first visit, 6month, 1year, 3year, 5year time point after drug cessation in eyes with chloroquine retinal toxicity Retrospective chart review from medical record

Secondary Outcome Measures

Name	Time	Method
Proportion of the progression of maculopathy after the drug cessations At first visit, 6month, 1year, 3year, 5year time point after drug cessation in eyes with chloroquine retinal toxicity Retrospective chart review from medical record,Fundus autofluorescence and full-field electroretinography change in chloroquine maculopathy after the drug cessations At first visit, 6month, 1year, 3year, 5year time point after drug cessation in eyes with chloroquine retinal toxicity Retrospective chart review from medical record