Melatonin ischemic stroke
Phase 2
Recruiting
- Conditions
- Cerebellar stroke syndrome.Cerebellar stroke syndromeG46.4
- Registration Number
- IRCT20190804044429N10
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Adults over the age of 18 and diagnose with acute ischemic stroke according to brain CT scan findings
NIHSS more than 4
Exclusion Criteria
Hemorrhagic stroke
Lacunar infarct
TIA
NIHSS more than 25
Pregnancy
Lactation
Severe hepatic insufficiency
History of apnea
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Glutathione serum level. Timepoint: days 0 and 5th of the study. Method of measurement: Spectroscopy.;Antioxidant serum levels. Timepoint: at days 0 and 5th of the study. Method of measurement: Spectroscopy.
- Secondary Outcome Measures
Name Time Method Disability following stroke. Timepoint: At days 0, discharge and month three of the study. Method of measurement: According to mRS.;Tolerability of melatonin. Timepoint: During the study period. Method of measurement: History taking.