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Clinical Trials/ITMCTR2100005164
ITMCTR2100005164Completed未知

Drug-drug interaction between Zuojin pill and venlafaxine based on CYP2D6 activity

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine0 sitesStarted: TBDLast updated:
Conditions

Trial Snapshot

Phase
未知
Status
Completed
Sponsor

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional study

Eligibility Criteria

Ages
21 to 26 (—)
Sex
Male

Inclusion Criteria

  • 1. Aged 19 to 45 years;
  • 2. The body weight is greater than 50kg, and the body mass index [weight kg/ (height m) 2] is between 19 and 24;
  • 3. Good health condition(no significant clinical symptoms or clinically significant abnormal laboratory results).

Exclusion Criteria

  • 1. Allergic physique, with a history of drug or food allergy;
  • 2. Heart, liver, kidney disease or acute or chronic digestive tract disease, angle-closure glaucoma, epilepsy, thyroid disease, blood disease.Or other acute or chronic diseases that may affect drug absorption and metabolism;
  • 3. Positive hepatitis B surface antigen;
  • 4. Drug abusers and tobacco and alcohol abusers;
  • 5. Drinking alcohol within 36 hours before the test;
  • 6. Blood loss or blood donation of more than 200 ml within 3 months before the test;
  • 7. Taking other drugs within 2 weeks before the test;
  • 8. According to the judgment of the researcher, those who are less likely to be included (such as weak body, etc.).

Investigators

Sponsor
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

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