Enhancing Prospective Thinking in Early Recovery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Alcohol Use Disorder
- Sponsor
- Indiana University
- Enrollment
- 21
- Locations
- 1
- Primary Endpoint
- Increase Prospective Thinking
- Status
- Recruiting
- Last Updated
- 3 months ago
Overview
Brief Summary
The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use disorder persons and related brain mechanisms. The main question[s] this trial aims to answer are:
- Will high-intensity EFT cues will produce greater delayed reward preference than low-intensity cues?
- Will high-intensity EFT cues effect greater treatment-seeking interest?
- Will high-intensity EFT cues elicit greater response in regions for prospective thinking during delay discounting (vs. low-intensity)
- Will nucleus accumbens-precuneus resting connectivity correlate with behavioral SS?
- Will the novel behavioral SS decision-making task activate the nucleus accumbens?
Researchers will compare the experimental (high-intensity group) and control (low-intensity) groups to see if there are differences in the results for the questions outlined above.
Investigators
Brandon G. Oberlin, PhD
Assistant Professor
Indiana University
Eligibility Criteria
Inclusion Criteria
- •Individuals who meet current heavy drinking (≥2 heavy drinking days/month OR ≥7 drinks/week for biological females, and ≥14 drinks/week if biological male \[NIAAA definition\] and/or AUDIT scores ≥8)
- •English comprehension
Exclusion Criteria
- •Unstable medical disorders
- •Outside the age range of 18-60
- •Smell/taste disorders
- •Unstable psychiatric conditions
Outcomes
Primary Outcomes
Increase Prospective Thinking
Time Frame: Study Day Visit (Day 1)
High-intensity episodic future-thinking image cues will change prospective thinking.
Delayed Rewards
Time Frame: Study Day Visit (Day 1)
High-intensity episodic future-thinking image cues will change preference for delayed rewards, which will be measured using a behavioral delayed discounting task.