Enhancing Prospective Thinking in Early Recovery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Alcohol Use Disorder
- Sponsor
- Indiana University
- Enrollment
- 58
- Locations
- 1
- Primary Endpoint
- Increase Prospective Thinking
- Status
- Completed
- Last Updated
- 5 months ago
Overview
Brief Summary
The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use disorder persons and related brain mechanisms. The main question[s] this trial aims to answer are:
Will high-intensity EFT cues will produce greater delayed reward preference than low-intensity cues? Will high-intensity EFT cues effect greater treatment-seeking interest? Will high-intensity EFT cues elicit greater response in regions for prospective thinking during delay discounting (vs. low-intensity) Will nucleus accumbens-precuneus resting connectivity correlate with behavioral SS? Will the novel behavioral SS decision-making task activate the nucleus accumbens? Researchers will compare the experimental (high-intensity group) and control (low-intensity) groups to see if there are differences in the results for the questions outlined above.
Investigators
Brandon G. Oberlin, PhD
Assistant Professor
Indiana University
Eligibility Criteria
Inclusion Criteria
- •Abstinence between 30 days ≤ 1 year
- •Verbal endorsement of commitment to recovery
- •English comprehension
Exclusion Criteria
- •Unstable medical disorders
- •Outside the age range of 18-60
- •Habitual substance or alcohol use
- •Smell/taste disorders
- •Unstable psychiatric conditions
Outcomes
Primary Outcomes
Increase Prospective Thinking
Time Frame: [Time Frame: Study Day Visit (Day 1)]
High-intensity episodic future-thinking image cues will increase prospective thinking.
Delayed Rewards
Time Frame: [Time Frame: Study Day Visit (Day 1)]
High-intensity episodic future-thinking image cues will change preference for delayed rewards, which will be measured using a behavioral delayed discounting task.