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Clinical Trials/NCT06283446
NCT06283446
Completed
Not Applicable

Enhancing Prospective Thinking in Early Recovery

Indiana University1 site in 1 country58 target enrollmentAugust 31, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Alcohol Use Disorder
Sponsor
Indiana University
Enrollment
58
Locations
1
Primary Endpoint
Increase Prospective Thinking
Status
Completed
Last Updated
5 months ago

Overview

Brief Summary

The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use disorder persons and related brain mechanisms. The main question[s] this trial aims to answer are:

Will high-intensity EFT cues will produce greater delayed reward preference than low-intensity cues? Will high-intensity EFT cues effect greater treatment-seeking interest? Will high-intensity EFT cues elicit greater response in regions for prospective thinking during delay discounting (vs. low-intensity) Will nucleus accumbens-precuneus resting connectivity correlate with behavioral SS? Will the novel behavioral SS decision-making task activate the nucleus accumbens? Researchers will compare the experimental (high-intensity group) and control (low-intensity) groups to see if there are differences in the results for the questions outlined above.

Registry
clinicaltrials.gov
Start Date
August 31, 2023
End Date
July 31, 2025
Last Updated
5 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Brandon G. Oberlin, PhD

Assistant Professor

Indiana University

Eligibility Criteria

Inclusion Criteria

  • Abstinence between 30 days ≤ 1 year
  • Verbal endorsement of commitment to recovery
  • English comprehension

Exclusion Criteria

  • Unstable medical disorders
  • Outside the age range of 18-60
  • Habitual substance or alcohol use
  • Smell/taste disorders
  • Unstable psychiatric conditions

Outcomes

Primary Outcomes

Increase Prospective Thinking

Time Frame: [Time Frame: Study Day Visit (Day 1)]

High-intensity episodic future-thinking image cues will increase prospective thinking.

Delayed Rewards

Time Frame: [Time Frame: Study Day Visit (Day 1)]

High-intensity episodic future-thinking image cues will change preference for delayed rewards, which will be measured using a behavioral delayed discounting task.

Study Sites (1)

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