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Clinical Trials/NCT06302413
NCT06302413
Recruiting
Not Applicable

Enhancing Prospective Thinking in Early Recovery

Indiana University1 site in 1 country500 target enrollmentFebruary 15, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Alcohol Use Disorder
Sponsor
Indiana University
Enrollment
500
Locations
1
Primary Endpoint
Increased Length of Abstinence
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The goal of this clinical trial is to use a novel virtual reality intervention to test for efficacy in reducing alcohol use and increasing abstinence, with concomitant increases in future self-identification, future time perspective, and delay-of-reward, in early recovering alcohol use disorder (AUD) persons. The main question[s] this trial aims to answer are:

Will the Virtual Reality (VR) intervention decrease the number of stimulant use days? Will the VR intervention produce longer abstinence periods during follow-up visits? Will the VR intervention increase alcohol abstinence rates? Will the VR intervention increase future self-identification? Will the VR intervention increase self-reported future time perspective? Will the VR intervention increase preference for delayed rewards in a laboratory delay discounting task on the study day? Will the VR intervention produce gains in the behavioral effects of future self-identification, future time perspective, and delayed rewards at the 30-day and 6-month follow-ups? Researchers will compare the experimental and control groups to see if there are differences in the results for the questions outlined above.

Registry
clinicaltrials.gov
Start Date
February 15, 2024
End Date
July 31, 2027
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Brandon G. Oberlin, PhD

Assistant Professor

Indiana University

Eligibility Criteria

Inclusion Criteria

  • Abstinence between ≥14 days and ≤1 year
  • Verbal endorsement of commitment to recovery
  • Outpatient
  • Psychotropic drugs for SUD-comorbidity
  • Drug/alcohol abstinence ≥ 24 hours at the time of the study day visit
  • English comprehension

Exclusion Criteria

  • Unstable medical disorders
  • Habitual drug use
  • Mu-opioid drugs
  • Smell/taste disorders
  • Unstable psychiatric conditions
  • Extravagant/elaborate face tattoos

Outcomes

Primary Outcomes

Increased Length of Abstinence

Time Frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.

The Virtual Reality Avatar experience will increase the length of abstinence periods.

Future Time Perspective with the Delayed Discounting Behavioral Task and Future Self Continuity Questionnaire

Time Frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.

The Virtual Reality Avatar experience will increase future time perspective.

Reduced Use of Drug Using Days

Time Frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit

The Virtual Reality Avatar experience will reduce drug using days.

Increased (overall) Abstinence

Time Frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.

The Virtual Reality Avatar experience will increase abstinence.

Delayed Reward Preference with the Delayed Discounting Behavioral Task

Time Frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.

The Virtual Reality Avatar experience will increase preference for delayed rewards.

Future Self-identification with Future Self Continuity Questionnaire

Time Frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit

The Virtual Reality Avatar experience will increase future self-identification.

Study Sites (1)

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