Enhancing Prospective Thinking in Early Recovery (HOME)

Not Applicable

Recruiting

• Conditions: Alcohol Use Disorder

• Registration Number: NCT06302413
• Lead Sponsor: Indiana University

Brief Summary

The goal of this clinical trial is to use a novel virtual reality intervention to test for efficacy in reducing alcohol use and increasing abstinence, with concomitant increases in future self-identification, future time perspective, and delay-of-reward, in early recovering alcohol use disorder (AUD) persons. The main question\[s\] this trial aims to answer are:

Will the Virtual Reality (VR) intervention decrease the number of stimulant use days? Will the VR intervention produce longer abstinence periods during follow-up visits? Will the VR intervention increase alcohol abstinence rates? Will the VR intervention increase future self-identification? Will the VR intervention increase self-reported future time perspective? Will the VR intervention increase preference for delayed rewards in a laboratory delay discounting task on the study day? Will the VR intervention produce gains in the behavioral effects of future self-identification, future time perspective, and delayed rewards at the 30-day and 6-month follow-ups? Researchers will compare the experimental and control groups to see if there are differences in the results for the questions outlined above.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-02-15
• Study First Submitted: 2024-02-21
• Study First Submitted QC: 2024-03-04
• Study First Posted: 2024-03-08
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-19
• Last Update Posted: 2025-03-24
• Primary Completion: 2027-07-31
• Study Completion: 2027-07-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• Abstinence between ≥14 days and ≤1 year
• Verbal endorsement of commitment to recovery
• Outpatient
• Psychotropic drugs for SUD-comorbidity
• Drug/alcohol abstinence ≥ 24 hours at the time of the study day visit
• English comprehension

Exclusion Criteria

• Unstable medical disorders
• Habitual drug use
• Mu-opioid drugs
• Smell/taste disorders
• Unstable psychiatric conditions
• Extravagant/elaborate face tattoos

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Increased Length of Abstinence	Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.	The Virtual Reality Avatar experience will increase the length of abstinence periods.
Future Time Perspective with the Delayed Discounting Behavioral Task and Future Self Continuity Questionnaire	Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.	The Virtual Reality Avatar experience will increase future time perspective.
Reduced Use of Drug Using Days	Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit	The Virtual Reality Avatar experience will reduce drug using days.
Increased (overall) Abstinence	Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.	The Virtual Reality Avatar experience will increase abstinence.
Delayed Reward Preference with the Delayed Discounting Behavioral Task	Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.	The Virtual Reality Avatar experience will increase preference for delayed rewards.
Future Self-identification with Future Self Continuity Questionnaire	Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit	The Virtual Reality Avatar experience will increase future self-identification.

Trial Locations

Locations (1)

Indiana University School of Medicine - Goodman Hal; 🇺🇸 Indianapolis, Indiana, United States