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Enhancing Prospective Thinking in Early Recovery (BEAM)

Not Applicable
Completed
Conditions
Alcohol Use Disorder
Registration Number
NCT06283472
Lead Sponsor
Indiana University
Brief Summary

The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use disorder persons and related brain mechanisms. The main question\[s\] this trial aims to answer are:

* Will high-intensity EFT cues will produce greater delayed reward preference than low-intensity cues?

* Will high-intensity EFT cues effect greater treatment-seeking interest?

* Will high-intensity EFT cues elicit greater response in regions for prospective thinking during delay discounting (vs. low-intensity)

* Will nucleus accumbens-precuneus resting connectivity correlate with behavioral SS?

* Will the novel behavioral SS decision-making task activate the nucleus accumbens?

Researchers will compare the experimental (high-intensity group) and control (low-intensity) groups to see if there are differences in the results for the questions outlined above.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
21
Inclusion Criteria
  • Individuals who meet current heavy drinking (≥2 heavy drinking days/month OR ≥7 drinks/week for biological females, and ≥14 drinks/week if biological male [NIAAA definition] and/or AUDIT scores ≥8)
  • English comprehension
Exclusion Criteria
  • Unstable medical disorders
  • Outside the age range of 18-60
  • Smell/taste disorders
  • Unstable psychiatric conditions

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Increase Prospective ThinkingStudy Day Visit (Day 1)

High-intensity episodic future-thinking image cues will change prospective thinking.

Delayed RewardsStudy Day Visit (Day 1)

High-intensity episodic future-thinking image cues will change preference for delayed rewards, which will be measured using a behavioral delayed discounting task.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Indiana University School of Medicine - Goodman Hall

🇺🇸

Indianapolis, Indiana, United States

Indiana University School of Medicine - Goodman Hall
🇺🇸Indianapolis, Indiana, United States

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