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Post-Marketing Non-Acute Safety Study in Japan After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA-1273 COVID-19 Vaccine in Persons at High Risk of Severe COVID-19

Completed
Conditions
SARS-CoV-2
Registration Number
NCT05894590
Lead Sponsor
ModernaTX, Inc.
Brief Summary

The goal of this study is to assess serious adverse events associated with hospitalizations in the non-acute phase after vaccination with the mRNA-1273 vaccine in persons with underlying diseases who are considered to have a high risk of severe exacerbation of COVID-19.

Detailed Description

Data collected from the JMDC Claims database from May 2020 to October 2022.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
13680
Inclusion Criteria
  • Participants registered to receive the mRNA-1273 vaccine in the Pep Up vaccination history Database
  • Participants who have a history of vaccination with the mRNA-1273 vaccine in the Pep-Up vaccination history Database and the observation start date is at least 6 months prior to vaccination with the mRNA-1273 vaccine and have underlying diseases.
Exclusion Criteria
  • Underlying diseases that were determined undetectable by the pre-screening of JMDC
  • Participants who did not consent to the questionnaire.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Number of Participants With Serious Events Associated With all-Cause HospitalizationsUp to 1 year post vaccination
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

CMIC Co., Ltd

🇯🇵

Tokyo, Japan

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