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Post-Marketing Safety Study in Japan in Participants With High Risk of Severe Exacerbation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA-1273 COVID-19 Vaccine

Completed
Conditions
SARS-CoV-2
Registration Number
NCT05894525
Lead Sponsor
ModernaTX, Inc.
Brief Summary

The goal of this study is to assess the adverse events in the acute phase observed after vaccination with the mRNA-1273 vaccine in persons with underlying diseases who are considered to have a high risk of severe exacerbation specified in COVID-19.

Detailed Description

Data collected from the JDMC Claims Database between August 2020 to November 2021.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
8844
Inclusion Criteria
  • Participants registered to receive the mRNA-1273 vaccine in the Pep Up vaccination history Database
  • Participants who have a history of vaccination with the mRNA-1273 vaccine in the Pep-Up vaccination history Database and have underlying diseases. Data period for confirmation of presence/absence of underlying disease is August 2020 to November 2021.
Exclusion Criteria
  • Underlying diseases that were determined undetectable by the pre-screening of JMDC
  • Participants who did not consent to the questionnaire

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Number of Participants With Solicited Acute Adverse EventsUp to 8 days post vaccination
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

CMIC Co. Ltd.,

🇯🇵

Tokyo, Japan

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