Comparing Montiroing Cardiac Index by Transpulmonary Thermodilution and Transesophageal Echocardiography During Liver Transplantation

Recruiting

• Conditions: Liver Transplantation

• Registration Number: NCT06899867
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Liver transplantation poses challenges due to hemodynamic changes throughout different surgical phases. Monitoring devices are essential for therapeutic adjustments. Transpulmonary thermodilution and transesophageal echocardiography are commonly used, but thermodilution may have limitations depending on the surgery.

This study aims to compare cardiac index variations between thermodilution and transesophageal echocardiography during liver transplantation. Patients undergo monitoring with both techniques. Measurements are recorded and reported at multiple time points.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-11-27
• Primary Completion: 2024-07-01
• Status Verified: 2025-03
• Study First Submitted: 2025-03-21
• Study First Submitted QC: 2025-03-21
• Last Update Submitted: 2025-03-21
• Study First Posted: 2025-03-28
• Last Update Posted: 2025-03-28
• Study Completion: 2025-11-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• liver transplantation
• adults

Exclusion Criteria

• • Oesophageal varice ligation < 14 days
• Mediastinal radiotherapy
• Femoral bypass
• Severe lower extremity artery disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cardiac index variation measured by thermodilution compared with transesophageal echography	At 4 times of surgery: after starting anesthesia, anhepatic phase, reperfusion and surgical anastomosis of biliary ducts. Data reported : - Cardiac Index before and after end-expiratory test. - Transoesophageal echography measurement of cardiac function

Trial Locations

Locations (1)

Croix Rousse Hsopital; 🇫🇷 France, Lyon, France

Croix Rousse Hsopital

🇫🇷France, Lyon, France

BLET Alice, MD,PhD

Contact

371239

alice.blet@chu-lyon.fr