Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block

Phase 1

Recruiting

• Conditions: Hip Fractures; Post Operative Pain
• Interventions: Drug: Pericapsular Nerve Group (PENG) Block

• Registration Number: NCT06294665
• Lead Sponsor: Ain Shams University

Brief Summary

The aim of this work is to compare the effectiveness of bupivacaine- dexmedetomidine mixture versus bupivacaine-dexamethasone mixture in PENG Block as Post-operative Analgesia in Hip surgeries

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-02
• Study First Submitted: 2024-02-28
• Study First Submitted QC: 2024-02-28
• Last Update Submitted: 2024-02-28
• Study Start: 2024-03-01
• Study First Posted: 2024-03-05
• Last Update Posted: 2024-03-05
• Primary Completion: 2024-12-01
• Study Completion: 2025-01-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Age 18-65 years.
2. Sex: Both sexes.
3. American Society of Anaesthesiologists (ASA) Physical Status Class I and II.
4. Scheduled for hip surgeries under spinal anaesthesia.

Exclusion Criteria

1. Declining to give written informed consent.
2. History of allergy to the medications used in the study.
3. Contraindications to regional anesthesia (including patient refusal, coagulopathy and local infection).
4. Psychiatric disorder.
5. American Society of Anesthesiologists (ASA) Physical Status Class III and IV.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group A : ( Bupivacaine + Dexmedetomidine )	Pericapsular Nerve Group (PENG) Block	Group A : will receive bupivacaine 0.25% + dexmedetomidine 1 mic/kg, total volume (20 ml)
Group B: ( Bupivacaine + Dexamethasone )	Pericapsular Nerve Group (PENG) Block	Group B : will receive bupivacaine 0.25% +dexamethasone (8 mg), total volume(20 ml).

Primary Outcome Measures

Name	Time	Method
The time to the first request of analgesia	9 months	The time interval between the onset of the local infiltration done at the end of the operation and the first request to postoperative analgesia.

Secondary Outcome Measures

Name	Time	Method
Total doses of analgesia (Nalbuphine) given to patients in 24 hours postoperatively	9 months
Occurrence of side effects of drugs.	9 months

Trial Locations

Locations (1)

Ain Shams University; 🇪🇬 Cairo, Egypt