Comparison of Several Oxygenation Targets With Different Oxygen Interfaces - Impact on Oxygen Flow Rates
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Oxygen flow
研究概览
简要总结
Oxygen therapy is at the heart of the healthcare system. Oxygen flow rates depend on a number of confounding factors confounding factors (target used, skin pigmentation, pulse oximeter used, etc.) The investigators have recently have recently demonstrated that the combination of these factors (different peripheral oxygen saturation (SpO2) targets and different oximeters) can have a significant impact on oxygen flows rates. The effect on oxygen flow was not simply additive .
The aim of this study is to evaluate the impact of the interface used on oxygen flow rates in different patient populations (main objective). The investigatoers also evaluate the impact of the interface on carbon dioxide (PaCO2), in particular with closed oxygen masks, with which rebreathing is theoretically possible (secondary objective).
secondary objective).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult (> or = 18 years old)
- •Ongoing on conventional oxygen therapy with peripheral oxygen saturation (SpO2) between 88 and 100% with the usual oximeter
- •SpO2 < 92% ambient air with the usual oximeter
排除标准
- •No SpO2 signal with with the usual oximeter
- •False nails or nail polish
- •Severe anemia documented on last blood count during current hospitalization (haemoglobin (Hb) < 80g/L)
- •Oxygen flow > 6 L/min
研究组 & 干预措施
Nellcor oximeter
干预措施: Nasal canula - up to 15 liters per minute (Device)
Nellcor oximeter
干预措施: Nasal canula - up to 6 liters per minute (Device)
Nellcor oximeter
干预措施: Open oxygen mask (Device)
Nellcor oximeter
干预措施: Simple oxygen face mask (Device)
Nonin Oximeter
干预措施: Nasal canula - up to 6 liters per minute (Device)
结局指标
主要结局
Oxygen flow
时间窗: Mean Oxygen flow in the five last minute of each study period (between minute 10 and 15)
Oxygen flows (or fraction of inspired oxygen (FiO2)) at the end of each study period (last minute average) to reach peripheral oxygen saturation (SpO2) target to reach SpO2 target with specific oxygen administration interfaces
次要结局
- Partial oxygen weaning(Mean oxygen flow in the five last minute of each study period (between minute 10 and 15))
- Complete oxygen weaning(Mean oxygen flow in the five last minute of each study period (between minute 10 and 15))
研究者
François Lellouche
Principal Investigator
Laval University