analgesic effect of intravenous ketamine

Phase 3

Conditions: Condition 1: Upper or Lower limb fracture. Condition 2: Upper or Lower limb dislocation.
Fracture of upper limb, level unspecified, Fracture of lower limb, level unspecified
Dislocation, sprain and strain of unspecified joint and ligament of upper limb or lower limb, level unspecified
T10, T12
T11.2, T13

Registration Number: IRCT2015122225660N1

Lead Sponsor: Vice chancellor for research,Arak University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 606

Inclusion Criteria

Patients with isolated trauma with fracture in the upper or lower extremities; aged between 15 and 55 years old; with Visual Analogue Scale pain score of more than 50 mm.
Exclusion criteria: Patient’s refusal to participate in the study; having an underlying medical condition such as migraine, cardiac ischemia, schizophrenia, history of allergy to opiates or ketamine, head trauma or loss of consciousness; blood pressure of more than 180/100; vital signs Instability before and during the study; pregnancy; any inability to express their pain during the study; presence of other trauma.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain severity. Timepoint: 0, 5th,10th, 20th minute. Method of measurement: Visual analog scale.

Secondary Outcome Measures

Name	Time	Method
Dizziness, nausea, burning throat, amnesia, headache,. Timepoint: Before intervention, 5, 10 and 20 minutes after intervention. Method of measurement: physical examination.;Need for rescue analgesia. Timepoint: 20 minutes after intervention. Method of measurement: Visual analog scale of pain.