NCT07018778尚未招募不适用
Quantification of Myocardial Blood Flow in Cardiovascular Magnetic Resonance for Prediction of Fractional Flow Reserve in Coronary Catheterisation
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Quantitative Perfusion
研究概览
简要总结
Patients will undergo quantitative perfusion assessment in cardiovascular magnetic resonance imaging (dual bolus or dual sequence approach) as well as invasive coronary angiography for assessment of fractional flow reserve (FFR) including assessment of coronary flow reserve (CFR) and microcirculatory resistance (IMR).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •clinical indication for vasodilatator CMR or invasive coronar angiography
- •capability to give informed consent
排除标准
- •general: non-compliance, <18 years of age, pregnancy
- •contraindications for CMR (non-CMR compatible device, chronic kidney disease (eGFR <30ml/min), allergies (medications)
结局指标
主要结局
Quantitative Perfusion
时间窗: assessment of CMR and invasive data within 24hours
Correlation of myocardial blood flow and perfusion reserve in CMR with invasively dervived fractional flow reserve (FFR), coronary flow reserve (CFR) and microcirculatory resistance (IMR)
Dual bolus vs dual sequence
时间窗: assessment of CMR and invasive data within 24hours
Compare both CMR-derived quantitative perfusion for prediction of FFR/CFR/IMR
次要结局
- Strain(baseline CMR data)
- Tissue characterisation(baseline CMR data)
- Cardiovascular Hospitalisation (CVH)(12 months)
研究者
研究点 (1)
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