The effect of riluzole on spinal cord injury
Phase 2
- Conditions
- Spinal injury.Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
- Registration Number
- IRCT2014031813947N3
- Lead Sponsor
- Vice Chancellor for research of Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1. acute spinal cord injury with Frankel Impairment Scale level A to C;
2. 18 to 70 years old;
3. Informed consent;
4. C4 to L2 vertebral fractures
Exclusion criteria:
1. Hepatic or renal disorders;
2. Penetrating brain trauma;
3. Traumatic brain injury;
4. Pregnancy or Breastfeeding;
5. Recent alcohol consumption;
6. Neurological or psychiatric disorders;
7. Life threatening injuries;
8. Unable to receive riluzole orally
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sensory injury. Timepoint: Primary, 6 weeks and 6 months following end of treatment. Method of measurement: Frankel classification.;Motor injury. Timepoint: Primary, 6 weeks and 6 months following end of treatment. Method of measurement: Frankel classification.;Pain. Timepoint: Primary, 6 weeks and 6 months following end of treatment. Method of measurement: Visual Analog Scale.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: Primary, 6 weeks and 6 months following end of treatment. Method of measurement: Physical examination.