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Clinical Trials/NCT06561945
NCT06561945
Not yet recruiting
Not Applicable

Accuracy of Dental Movements Using Clear Aligners Treatment: a Single-center Prospective Observational Study

IRCCS Ospedale San Raffaele0 sites100 target enrollmentNovember 1, 2024
ConditionsMalocclusion

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Malocclusion
Sponsor
IRCCS Ospedale San Raffaele
Enrollment
100
Primary Endpoint
Evaluate accuracy aligners of on transversal dental linear movements
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

The aim of the present prospective observational study is to evaluate the accuracy of dental movements in the three planes of space, assessing the correspondence between the virtual planned movements and the clinical outcomes achieved using thermoformed or 3D printed orthodontic aligners. The study will include patients who are candidates for aligner orthodontics treatment. After having acquired the standard initial diagnostic data (clinical examination, intra- and extra-oral photographs, intra- and extra-oral scans, orthopantomography and lateral-lateral teleradiography of the skull), the digital impressions of the arches will be used to plan the dental movements necessary for correction of malocclusion.

The aligners will then be designed using orthodontic CAD software and realized using a thermoformed and direct 3D printing process.

All patients will be treated following current recommendations relating to the orthodontic treatments in question. After delivery of the aligners, during each check-up, intra-oral and extra-oral scans will be acquired to evaluate the actual position of the teeth and, using special software will be compare the virtually designed position with tooth with the clinical outcomes. Any discrepancies will be recorded and statistically analyzed.There are no additional invasive procedures. Intra- and extra-oral scans will be acquired regularly to monitor the extent of tooth movement over time.

Registry
clinicaltrials.gov
Start Date
November 1, 2024
End Date
September 1, 2028
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
IRCCS Ospedale San Raffaele
Responsible Party
Principal Investigator
Principal Investigator

Giorgio Gastaldi

Associate Professor

IRCCS Ospedale San Raffaele

Eligibility Criteria

Inclusion Criteria

  • Age between 18 and 65 years
  • Good general health
  • Presence of a dental/skeletal malocclusion
  • Permanent dentition with second molars completely erupted in the arch
  • Correct tooth shape, with sufficient height of the clinical crowns
  • Good compliance during treatment

Exclusion Criteria

  • Systemic diseases or pharmacological therapy with drugs that can affect orthodontic movement
  • Orofacial malformations or syndromes
  • Periodontal disease
  • Signs and/or symptoms of temporomandibular disorders
  • Absence of teeth (except for third molars)
  • Dental Implants

Outcomes

Primary Outcomes

Evaluate accuracy aligners of on transversal dental linear movements

Time Frame: 18 months

Correspondence between virtual planned linear movements (in millimetres) and clinical outcomes achieved using aligners evaluated on the transversal plane. Post-treatment digital models and final virtual treatment plan models will be exported as STL files and subsequently imported into Geomagic Qualify ®software, to compare final teeth positions

Evaluate accuracy aligners of on vertical dental linear movements

Time Frame: 18 months

Correspondence between virtual planned linear movements (in millimetres) and clinical outcomes achieved using aligners evaluated on the vertical plane. Post-treatment digital models and final virtual treatment plan models will be exported as STL files and subsequently imported into Geomagic Qualify ®software, to compare final teeth positions

Evaluate accuracy aligners of on sagittal dental linear movements

Time Frame: 18 months

Correspondence between virtual planned linear movements (in millimetres) and clinical outcomes achieved using aligners evaluated on the sagittal plane. Post-treatment digital models and final virtual treatment plan models will be exported as STL files and subsequently imported into Geomagic Qualify ®software, to compare final teeth positions

Secondary Outcomes

  • Evaluate accuracy of 3d printed aligners on sagittal dental angular movements(18 months)
  • Evaluate accuracy of 3d printed aligners on vertical dental angular movements(18 months)
  • Evaluate accuracy of 3d printed aligners on transversal dental angular movements(18 months)

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