Acetaminophen vs Ibuprofen in treatment of patent ductus arteriosus in premature infants with very low weight
Not Applicable
Recruiting
- Conditions
- patent ductus arteriosus.Patent ductus arteriosusQ25.0
- Registration Number
- IRCT20230828059282N1
- Lead Sponsor
- Oroumia University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Prematurity
Not physiologicaly closed patent ductus arteriosus
Very low weight
Exclusion Criteria
Sepsis
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Closed ductus arteriosus. Timepoint: 3,6,9,12 days from initial treatment. Method of measurement: Echocardiography.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How do the molecular mechanisms of parenteral acetaminophen and oral ibuprofen differ in PDA closure in VLBW infants?
What is the comparative efficacy of parenteral acetaminophen versus oral ibuprofen as standard-of-care for PDA in VLBW infants?
Which biomarkers predict response to parenteral acetaminophen or oral ibuprofen in VLBW infants with PDA?
What are the adverse event profiles of parenteral acetaminophen and oral ibuprofen in VLBW infants with PDA?
Are there alternative NSAIDs or combination therapies to acetaminophen and ibuprofen for PDA in VLBW infants?