Effectiveness of adding allopurinol to the treatment of manic patients
- Conditions
- Mania.Manic episode
- Registration Number
- IRCT201202229111N1
- Lead Sponsor
- Research Center for Behavioral Disorders And Substance Abuse
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
All patients who are admitted to psychiatric wards of Farshchian Psychiatry Hospital, Hamedan, Iran, for acute phase of mania according to DSM IV-TR. Exclusion criteria: 1) General health priority; 2) Having other psychiatric diagnostics such as schizophrenia, anxiety disorders and etc; 3) Consumption of substance or dependence on alcohol during the past month; 4) Existence of prominent problem in their laboratory tests; 5) History of serious cardiac, respiratory, nervous, endocrine, kidney disease, and uncontrolled diabetes; 6) Pregnancy and breastfeeding; 7) Consumption of drugs such as Azathioprine, Mercaptopurine, Apalcillin, Amoxicillin, Ampicillin, Warfarin and Theophylline; 8) Sensitivity to Allopurinol; 9) The need for ECT during the treatment; 10) Having YMRS < 17.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mania. Timepoint: 1, 7, 14, 21, 28 days or at the end of treatment. Method of measurement: YMRS and CGI.
- Secondary Outcome Measures
Name Time Method ric acid. Timepoint: 1, 28 days or at the end of treatment. Method of measurement: Serum level.