A clinical trial to study the effects of two sedative drugs, propofol and dexmedetomidine on diaphragm, in patients undergoing surgery under regional anaesthesia.
Not Applicable
Completed
- Conditions
- Health Condition 1: B- Imaging
- Registration Number
- CTRI/2021/08/035454
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 126
Inclusion Criteria
1. ASA I or II patients
2. Age group of 18â??60 years
3. Scheduled for elective surgery
4. Requiring regional anesthesia, that doesnâ??t affect their diaphragmatic function
Exclusion Criteria
1. Patientâ??s refusal
2. Contraindication to regional anesthesia
3. History of hypersensitivity to propofol, dexmedetomidine, or local anesthetics
4. Neurologic or muscular disease
5. Patients on anticholinergic drugs
6. Patient receiving Premedications
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the Diaphragmatic Thickness Fraction (DTF) between patients under propofol <br/ ><br>and dexmedetomidine sedation during elective surgery under regional anesthesia.Timepoint: Throughout the intraoperative period and immediate post operative period.
- Secondary Outcome Measures
Name Time Method To compare between the two groups the following parameters: <br/ ><br>1. Diaphragmatic excursion <br/ ><br>2. Diaphragmatic velocity <br/ ><br>3. Time to return of diaphragmatic function after stopping sedationTimepoint: Throughout the intraoperative period and immediate post operative period.