Assessment of Health Related Quality of Life by SGRQ-I in patients with idiopathic pulmonary fibrosis

Not Applicable

• Conditions: Idiopathic Pulmonary Fibrosis

• Registration Number: JPRN-UMIN000011142
• Lead Sponsor: Graduate School of Medicine, Kyoto University

Brief Summary

mMRC dyspnea scale, the HADS anxiety or depression, and minimum oxygen saturation during a six-minute walk test significantly contributed to the Total and three components of the SGRQ-I. In multivariate Cox proportional-hazards analyses, the Total score of SGRQ-I predicted clinical deterioration independent of forced vital capacity, the six-minute walk distance, or partial pressure of arterial oxygen on room air.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-07-08
• Study Completion: 2017-05-26
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

Exclusion criteria included: (1) Patients with complication of malignant disease. But, the patients keeping remission for more than three years are eligible. ; (2) Patients with psychiatric disease or unstable mental status. (3) Patients with acute exacerbation of IPF, respiratory infection, or pneumothorax within 4 weeks.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Scores of SGRQ-I Serum MMP7 concentrations