Study the Effect of Water Kefir Consumption on the Gut Microbiome in Healthy Adults

Not Applicable

Recruiting

• Conditions: Probiotics; Healthy Diet; Gastrointestinal Microbiome

• Registration Number: NCT05657730
• Lead Sponsor: Lund University

Brief Summary

The goal of this intervention study is to analyse the microbiota composition after the water kefir consumption. The main questions are to evaluate the potential probiotic drink can have beneficial effect on the gut microbiota. Participants will consume the water kefir for two weeks and microbiota will be analysed. Researchers will compare the microbiota composition before and after consumption.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-11-09
• Study Start: 2022-11-10
• Status Verified: 2022-12
• Study First Submitted QC: 2022-12-11
• Last Update Submitted: 2022-12-11
• Study First Posted: 2022-12-20
• Last Update Posted: 2022-12-20
• Primary Completion: 2023-01-14
• Study Completion: 2023-04-14

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 63

Inclusion Criteria

• 18-65 years of age.
• must be able to complete the form digitally.

Exclusion Criteria

• must not be diagnosed with gastrointestinal diseases, autoimmune diseases or have diseases or medications that cause immune deficiency such as MS, type 1 diabetes, cancer or HIV.
• must not take antibiotics during the study period.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
16S metagenomics based measurement of the bacterial diversity (alpha- and beta diversity indices), and the composition (relative abundance of the bacterial taxa in each sample)	up to 24 weeks	Potential changes of microbiome after consumption of the water kefir will be assessed by analyzing the 16S metagenomics

Trial Locations

Locations (1)

Lund University; 🇸🇪 Lund, Skåne, Sweden