Comparative Evaluation Of Herbal Matcha Extract And 2 percent Chlorhexidine Gluconate On Periodontal Health Status A Clinico Microbiological Study
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- To reduce gingivitis and periodontitis by reducing plaque accumulation
研究概览
简要总结
Title- Comparative Evaluation Of Matcha Extract And 2% Chlorhexidine Gluconate On Periodontal Health Status- A Clinico-microbiological Study
Abstract:
Introduction: Gingivitis and Periodontitis are a multifactorial inflammatory disease of the oral cavity that results in alveolar bone destruction and is main reason for tooth loss. Matcha tea is a Japanese fine-powdered green tea commonly consumed due to its health-promoting benefits.
Methodology: It is double blinded randomised clinical trial study with 32 adult patient having mild to moderate gingivitis and periodontitis. They were divided into 2 groups each with 16 patients. Group A were given Matcha extract and Group B given 2% Chlorhexidine gluconate. All participants were brought to baseline. They were asked to use their particular group mouthrinse for rinsing twice a day for 1 min. Indices were taken at baseline, 7 days, 14 days and 28 days. MIC (Minimal Inhibitory Concentration) was checked for Matcha extract on both P.gingivalis and S.mutans bacteria. And Gingival crevicular fluid (GCF) were taken at baseline and after 28 days to check Colony forming unit (CFU) of the samples.
Results: Matcha mouthrinse significantly reduced inflammatory condition of gingivitis and periodontitis (p<0.05) and is comparable with 2% Chlorhexidine gluconate. In-vitro evaluation of Matcha extract at various concentration of MIC show its effectiveness on P.gingivalis and S.mutans.
Conclusion: To conclude Matcha mouthrinse may be recommended as an alternative mouthrinse for improving oral health status.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 35.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient willing to participate Patient with gingivitis and periodontitis Age group 35 to 55 years.
排除标准
- •Patient with major systemic disease Subjects with advanced periodontal inflammation or severe malalignment of teeth Individuals with any allergy or hypersensitivity to herbal medicine.
结局指标
主要结局
To reduce gingivitis and periodontitis by reducing plaque accumulation
时间窗: Baseline 7 days 14 days and 28 days
次要结局
- To compare two group & check effectiveness(Baseline 7 days 14 days 28 days)
研究者
Dr Ankita Vinayak Gadekar
JMFs A C P M Dental College Dhule